Functional suppression in mammalian cells of nonsense mutations in the herpes simplex virus thymidine kinase gene by suppressor tRNA genes.

A nonsense mutation (UAG) in the thymidine kinase gene of herpes simplex virus type 1 can be suppressed in vivo to produce active thymidine kinase by prior infection with a defective simian virus 40 stock which acts as a vector to introduce a functional suppressor tRNA gene into mammalian cells in c...

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Bibliographic Details
Published in:J Virol
Main Authors: Summers, W P, Summers, W C, Laski, F A, RajBhandary, U L, Sharp, P A
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1983
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC255271/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6312072/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.47.2.376-379.1983
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