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Insulin-induced Stimulation of Na(+),K(+)-ATPase Activity in Kidney Proximal Tubule Cells Depends on Phosphorylation of the α-Subunit at Tyr-10

Phosphorylation of the α-subunit of Na(+),K(+)-ATPase plays an important role in the regulation of this pump. Recent studies suggest that insulin, known to increase solute and fluid reabsorption in mammalian proximal convoluted tubule (PCT), is stimulating Na(+),K(+)-ATPase activity through the tyro...

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Published in:Mol Biol Cell
Main Authors: Féraille, Eric, Carranza, Maria Luisa, Gonin, Sandrine, Béguin, Pascal, Pedemonte, Carlos, Rousselot, Martine, Caverzasio, Joseph, Geering, Käthi, Martin, Pierre-Yves, Favre, Hervé
Format: Artigo
Language:Inglês
Published: American Society for Cell Biology 1999
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25522/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10473631/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.10.9.2847
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