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A Novel Ras-interacting Protein Required for Chemotaxis and Cyclic Adenosine Monophosphate Signal Relay in Dictyostelium

We have identified a novel Ras-interacting protein from Dictyostelium, RIP3, whose function is required for both chemotaxis and the synthesis and relay of the cyclic AMP (cAMP) chemoattractant signal. rip3 null cells are unable to aggregate and lack receptor activation of adenylyl cyclase but are ab...

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Detalhes bibliográficos
Main Authors: Lee, Susan, Parent, Carole A., Insall, Robert, Firtel, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC25521/
https://ncbi.nlm.nih.gov/pubmed/10473630
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