G/T Substitution in Intron 1 of the UNC13B Gene Is Associated With Increased Risk of Nephropathy in Patients With Type 1 Diabetes

OBJECTIVE— Genetic and environmental factors modulate the susceptibility to diabetic nephropathy, as initiating and/or progression factors. The objective of the European Rational Approach for the Genetics of Diabetic Complications (EURAGEDIC) study is to identify nephropathy susceptibility genes. We...

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Autori principali: Trégouet, David-Alexandre, Groop, Per-Henrik, McGinn, Steven, Forsblom, Carol, Hadjadj, Samy, Marre, Michel, Parving, Hans-Henrik, Tarnow, Lise, Telgmann, Ralph, Godefroy, Tiphaine, Nicaud, Viviane, Rousseau, Rachel, Parkkonen, Maikki, Hoverfält, Anna, Gut, Ivo, Heath, Simon, Matsuda, Fumihiko, Cox, Roger, Kazeem, Gbenga, Farrall, Martin, Gauguier, Dominique, Brand-Herrmann, Stefan-Martin, Cambien, François, Lathrop, Mark, Vionnet, Nathalie
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2008
Soggetti:
Genetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2551697/
https://ncbi.nlm.nih.gov/pubmed/18633107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-0073
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