Primer sets for cloning the human repertoire of T cell Receptor Variable regions

BACKGROUND: Amplification and cloning of naïve T cell Receptor (TR) repertoires or antigen-specific TR is crucial to shape immune response and to develop immuno-based therapies. TR variable (V) regions are encoded by several genes that recombine during T cell development. The cloning of expressed ge...

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Bibliografiske detaljer
Main Authors: Boria, Ilenia, Cotella, Diego, Dianzani, Irma, Santoro, Claudio, Sblattero, Daniele
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Methodology Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2551579/
https://ncbi.nlm.nih.gov/pubmed/18759974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-9-50
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