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Real-Time Imaging of the Axonal Transport of Granules Containing a Tissue Plasminogen Activator/Green Fluorescent Protein Hybrid

A hybrid protein, tPA/GFP, consisting of rat tissue plasminogen activator (tPA) and green fluorescent protein (GFP) was expressed in PC12 cells and used to study the distribution, secretory behavior, and dynamics of secretory granules containing tPA in living cells with a neuronal phenotype. High-re...

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Détails bibliographiques
Auteurs principaux: Lochner, Janis E., Kingma, Mary, Kuhn, Samuel, Meliza, C. Daniel, Cutler, Bryan, Scalettar, Bethe A.
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 1998
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC25514/
https://ncbi.nlm.nih.gov/pubmed/9725906
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