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Enhancement of the transforming capacity of BK virus by partial deletion of the 68-base-pair tandem repeats.

We constructed a set of deleted BK viral DNAs that lack part of the triplicated 68-base-pair (bp) sequences (the central unit has an 18-bp deletion) and assayed them for capacity to transform hamster kidney cells. Deletion of one of the two 68-bp units remarkably enhanced transforming capacity.

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Detalhes bibliográficos
Main Authors: Hara, K, Oya, Y, Yogo, Y
Formato: Artigo
Idioma:Inglês
Publicado em: 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC255077/
https://ncbi.nlm.nih.gov/pubmed/2991606
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