Phosphorylation of Sic1, a Cyclin-dependent Kinase (Cdk) Inhibitor, by Cdk Including Pho85 Kinase Is Required for Its Prompt Degradation

In the yeast Saccharomyces cerevisiae, Sic1, an inhibitor of Clb-Cdc28 kinases, must be phosphorylated and degraded in G(1) for cells to initiate DNA replication, and Cln-Cdc28 kinase appears to be primarily responsible for phosphorylation of Sic1. The Pho85 kinase is a yeast cyclin-dependent kinase...

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Detalhes bibliográficos

Publicado no:	Mol Biol Cell
Principais autores:	Nishizawa, Masafumi, Kawasumi, Masaoki, Fujino, Marie, Toh-e, Akio
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Cell Biology 1998
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25506/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9725902/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.9.9.2393
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