Genetic mapping of lymphocytic choriomeningitis virus pathogenicity: virulence in guinea pigs is associated with the L RNA segment.

The Armstrong CA 1371 (ARM) and WE strains of lymphocytic choriomeningitis virus (LCMV) differ in the ability to produce disease in adult guinea pigs. Infection with the ARM strain is not lethal, even at high virus doses (greater than 10,000 PFU), whereas the WE strain causes 100% mortality even at...

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Détails bibliographiques
Auteurs principaux: Riviere, Y, Ahmed, R, Southern, P J, Buchmeier, M J, Oldstone, M B
Format: Artigo
Langue:Inglês
Publié: 1985
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC255050/
https://ncbi.nlm.nih.gov/pubmed/4020963
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