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Protection of mice from wild-type Sendai virus infection by a trypsin-resistant mutant, TR-2.

A trypsin-resistant mutant of Sendai virus, TR-2, which could be activated by chymotrypsin but not by trypsin or the protease present in mouse lung, was inoculated intranasally into mice after being activated in vitro. TR-2 hardly brought about clinical illness or lung lesions in mice; the protease...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Tashiro, M, Homma, M
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC255018/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2981341/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.53.1.228-234.1985
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