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Genetic and biochemical analysis of transformation-competent, replication-defective simian virus 40 large T antigen mutants.

To study the role of the biochemical and physiological activities of simian virus 40 (SV40) large T antigen in the lytic and transformation processes, we have analyzed DNA replication-defective, transformation-competent T-antigen mutants. Here we describe two such mutants, C8/SV40 and T22/SV40, and...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Manos, M M, Gluzman, Y
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC254987/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2981330/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.53.1.120-127.1985
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