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Poliovirus protease 3C (P3-7c) does not cleave P220 of the eucaryotic mRNA cap-binding protein complex.

Infection of HeLa cells by poliovirus results in proteolysis of the large subunit (P220) of the cap-binding protein complex. This is believed to cause the rapid shut-off of host protein synthesis during poliovirus infection. In this communication we examined the possible involvement of poliovirus pr...

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Publicado en:J Virol
Autores principales: Lee, K A, Edery, I, Hanecak, R, Wimmer, E, Sonenberg, N
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1985
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC254958/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2991572/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.55.2.489-493.1985
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