Apolipoprotein E genotype and association between smoking and early onset Alzheimer's disease.

OBJECTIVE--To investigate the hypothesis that differential survival between smokers and non-smokers leading to a decrease in the frequency of the e4 allele of the apolipoprotein E gene may explain the inverse relation between smoking history and early onset Alzheimer's disease. DESIGN--A popula...

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Main Authors: van Duijn, C. M., Havekes, L. M., Van Broeckhoven, C., de Knijff, P., Hofman, A.
Format: Artigo
Jezik:Inglês
Izdano: BMJ Group 1995
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2549007/
https://ncbi.nlm.nih.gov/pubmed/7703749
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