Overcoming resistance to molecularly targeted anticancer therapies: rational drug combinations based on EGFR and MAPK inhibition for solid tumours and haematologic malignancies

Accumulating evidence suggests that cancer can be envisioned as a “signaling disease”, in which alterations in the cellular genome affect the expression and/or function of oncogenes and tumour suppressor genes. This ultimately disrupts the physiologic transmission of biochemical signals that normall...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Tortora, Giampaolo, Bianco, Roberto, Daniele, Gennaro, Ciardiello, Fortunato, McCubrey, James A, Ricciardi, Maria Rosaria, Ciuffreda, Ludovica, Cognetti, Francesco, Tafuri, Agostino, Milella, Michele
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2007
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2548422/
https://ncbi.nlm.nih.gov/pubmed/17482503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drup.2007.03.003
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