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Caenorhabditis elegans drp-1 and fis-2 regulate distinct cell death execution pathways downstream of ced-3 and independent of ced-9

The dynamin family of GTPases regulate mitochondrial fission and fusion processes and have been implicated in controlling the release of caspase activators from mitochondria during apoptosis. Here we report that profusion genes fzo-1 and eat-3, or the profission gene drp-1, are not required for apop...

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Detalhes bibliográficos
Main Authors: Breckenridge, David G., Kang, Byung-Ho, Kokel, David, Mitani, Shohei, Staehelin, L. Andrew, Xue, Ding
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2548325/
https://ncbi.nlm.nih.gov/pubmed/18722182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.07.015
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