A large-tumor-antigen-specific monoclonal antibody inhibits DNA replication of simian virus 40 minichromosomes in an in vitro elongation system.

In productively infected cells, a fraction of large-tumor antigen (T antigen) is tightly bound to replicating simian virus 40 (SV40) minichromosomes and does not dissociate at salt concentrations of greater than 1 M NaCl. We present electronmicrograms demonstrating the presence of T antigen on the r...

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Bibliographic Details
Published in:J Virol
Main Authors: Stahl, H, Dröge, P, Zentgraf, H, Knippers, R
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1985
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC254819/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2985809/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.54.2.473-482.1985
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