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Varying the position of a retrovirus packaging sequence results in the encapsidation of both unspliced and spliced RNAs.

By using a retroviral construct derived from Moloney murine leukemia virus and capable of expressing the dominant selectable neo gene, we measured the effects of moving or deleting a sequence (psi) known to be required in cis for the packaging of genomic RNA into virus particles. When psi was at its...

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Detalles Bibliográficos
Main Authors: Mann, R, Baltimore, D
Formato: Artigo
Idioma:Inglês
Publicado: 1985
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC254810/
https://ncbi.nlm.nih.gov/pubmed/3989912
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