Mechanical Stability of Helical β-Peptides and a Comparison of Explicit and Implicit Solvent Models

Synthetic β-peptide oligomers have been shown to form stable folded structures analogous to those encountered in naturally occurring proteins. Literature studies have speculated that the conformational stability of β-peptides is greater than that of α-peptides. Direct measurements of that stability,...

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Main Authors: Miller, Clark A., Gellman, Samuel H., Abbott, Nicholas L., de Pablo, Juan J.
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2008
Teme:
Biophysical Theory and Modeling
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2547455/
https://ncbi.nlm.nih.gov/pubmed/18621835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.134833
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