Role of Extracellular Glutamic Acids in the Stability and Energy Landscape of Bacteriorhodopsin

Bacteriorhodopsin (BR), a specialized nanomachine, converts light energy into a proton gradient to power Halobacterium salinarum. In this work, we analyze the mechanical stability of a BR triple mutant in which three key extracellular residues, Glu(9), Glu(194), and Glu(204), were mutated simultaneo...

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Hlavní autoři: Sapra, K. Tanuj, Doehner, Jana, Renugopalakrishnan, V., Padrós, Esteve, Muller, Daniel J.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2008
Témata:
Proteins
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2547453/
https://ncbi.nlm.nih.gov/pubmed/18621827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.131904
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