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Mutational mechanisms by which an inactive replication origin of bacteriophage M13 is turned on are similar to mechanisms of activation of ras proto-oncogenes.

M13 viral strand synthesis is initiated by nicking of the viral strand of the duplex replicative form by the M13 gene II initiator protein at a specific site within a sequence of about 40 base pairs having dyad symmetry. Efficient replication of the M13 viral strand also requires the presence of an...

詳細記述

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書誌詳細
出版年:J Virol
主要な著者: Kim, M H, Ray, D S
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 1985
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC254721/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3973968/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.53.3.871-878.1985
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