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Mitochondrial oxidative phosphorylation in autosomal dominant optic atrophy
BACKGROUND: Autosomal dominant optic atrophy (ADOA), a form of progressive bilateral blindness due to loss of retinal ganglion cells and optic nerve deterioration, arises predominantly from mutations in the nuclear gene for the mitochondrial GTPase, OPA1. OPA1 localizes to mitochondrial cristae in t...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2547100/ https://ncbi.nlm.nih.gov/pubmed/18783614 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-9-22 |
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