The Kinetics of Hepatitis C Virus-Specific CD8 T-Cell Responses in the Blood Mirror Those in the Liver in Acute Hepatitis C Virus Infection

Peripheral blood T-cell responses are used as biomarkers in hepatitis C virus (HCV) vaccine trials. However, it is not clear how T-cell responses in the blood correlate with those in the liver, the infection site. By studying serial liver and blood samples of five vaccinated and five mock-vaccinated...

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Bibliographic Details
Main Authors: Shin, Eui-Cheol, Capone, Stefania, Cortese, Riccardo, Colloca, Stefano, Nicosia, Alfredo, Folgori, Antonella, Rehermann, Barbara
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546987/
https://ncbi.nlm.nih.gov/pubmed/18667501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00475-08
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