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A Hyperfusogenic F Protein Enhances the Oncolytic Potency of a Paramyxovirus Simian Virus 5 P/V Mutant without Compromising Sensitivity to Type I Interferon

Viral fusogenic membrane proteins have been proposed as tools to increase the potency of oncolytic viruses, but there is a need for mechanisms to control the spread of fusogenic viruses in normal versus tumor cells. We have previously shown that a mutant of the paramyxovirus simian virus 5 (SV5) tha...

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Bibliografiska uppgifter
Huvudupphovsmän: Gainey, Maria D., Manuse, Mary J., Parks, Griffith D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 2008
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546974/
https://ncbi.nlm.nih.gov/pubmed/18667520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01054-08
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