Gag-Specific CD4(+) T-Cell Frequency Is Inversely Correlated with Proviral Load and Directly Correlated with Immune Activation in Infection with Human Immunodeficiency Virus Type 2 (HIV-2) but Not HIV-1

Human immunodeficiency virus type 2 (HIV-2) infection, unlike HIV-1 infection, is normally characterized by low rates of CD4 depletion and low-to-undetectable viremia. We found that the frequency of Gag-specific CD4(+) T cells featured positive correlations with the expression of markers of CD4 acti...

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Detalhes bibliográficos
Main Authors: Foxall, Russell B., Cortesão, Catarina S., Albuquerque, Adriana S., Soares, Rui S., Victorino, Rui M. M., Sousa, Ana E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546953/
https://ncbi.nlm.nih.gov/pubmed/18653457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01217-08
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