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CD44 Engagement Promotes Matrix-Derived Survival through the CD44-SRC-Integrin Axis in Lipid Rafts

CD44 is present in detergent-resistant, cholesterol-rich microdomains, called lipid rafts, in many types of cells. However, the functional significance of CD44 in lipid rafts is still unknown. We have previously demonstrated that osteopontin-mediated engagement of CD44 spliced variant isoforms promo...

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Détails bibliographiques
Auteurs principaux: Lee, Jia-Lin, Wang, Mei-Jung, Sudhir, Putty-Reddy, Chen, Jeou-Yuan
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2008
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546932/
https://ncbi.nlm.nih.gov/pubmed/18644869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00186-08
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