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The Anthrax Vaccine Adsorbed Vaccine Generates Protective Antigen (PA)-Specific CD4(+) T Cells with a Phenotype Distinct from That of Naïve PA T Cells

Cellular immune responses against protective antigen (PA) of Bacillus anthracis in subjects that received the anthrax vaccine adsorbed (AVA) vaccine were examined. Multiple CD4(+) T-cell epitopes within PA were identified by using tetramer-guided epitope mapping. PA-reactive CD4(+) T cells with a CD...

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Detalhes bibliográficos
Main Authors: Kwok, William W., Yang, Junbao, James, Eddie, Bui, John, Huston, Laurie, Wiesen, Andrew R., Roti, Michelle
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546819/
https://ncbi.nlm.nih.gov/pubmed/18678674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00324-08
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