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Enumeration of Cytotoxic CD8 T Cells Ex Vivo during the Response to Listeria monocytogenes Infection

Cytotoxicity is a key effector function of CD8 T cells. However, what proportion of antigen-specific CD8 T cells in vivo exert cytotoxic activity during a functional CD8 T-cell response to infection still remains unknown. We used the Lysispot assay to directly enumerate cytotoxic CD8 T cells from th...

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Detalhes bibliográficos
Main Authors: Zaiss, Dietmar M. W., Sijts, Alice J. A. M., Mosmann, Tim R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546808/
https://ncbi.nlm.nih.gov/pubmed/18678661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00563-08
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