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Polypyrimidine tract binding protein controls the transition from exon definition to an intron defined spliceosome
The polypyrimidine tract binding protein (PTB) binds pre-mRNAs to alter splice site choice. We characterized a series of spliceosomal complexes that assemble on a pre-mRNA under conditions of either PTB mediated splicing repression or its absence. In the absence of repression, exon-definition comple...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2546704/ https://ncbi.nlm.nih.gov/pubmed/18193060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1375 |
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