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Polypyrimidine tract binding protein controls the transition from exon definition to an intron defined spliceosome

The polypyrimidine tract binding protein (PTB) binds pre-mRNAs to alter splice site choice. We characterized a series of spliceosomal complexes that assemble on a pre-mRNA under conditions of either PTB mediated splicing repression or its absence. In the absence of repression, exon-definition comple...

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Bibliografski detalji
Glavni autori: Sharma, Shalini, Kohlstaedt, Lori A., Damianov, Andrey, Rio, Donald C., Black, Douglas L.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546704/
https://ncbi.nlm.nih.gov/pubmed/18193060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1375
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