Medea SUMOylation restricts the signaling range of the Dpp morphogen in the Drosophila embryo

Morphogens are secreted signaling molecules that form concentration gradients and control cell fate in developing tissues. During development, it is essential that morphogen range is strictly regulated in order for correct cell type specification to occur. One of the best characterized morphogens is...

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Autors principals: Miles, Wayne O., Jaffray, Ellis, Campbell, Susan G., Takeda, Shugaku, Bayston, Laura J., Basu, Sanjay P., Li, Mingfa, Raftery, Laurel A., Ashe, Mark P., Hay, Ronald T., Ashe, Hilary L.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2008
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546696/
https://ncbi.nlm.nih.gov/pubmed/18794353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.494808
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