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Polymer-level synthesis of oxopyrimidine deoxynucleotides by Bacillus subtilis phage SP10: characterization of modification-defective mutants.

Bacillus subtilis phage SP10 DNA has two oxopyrimidines, thymidine 5'-monophosphate (dTMP) and its hypermodified analog (YdTMP). Published data suggest that both are synthesized by postreplicational modification of 5-hydroxymethyldeoxyuridylate (HOMedUMP) in nascent DNA by the following pathway: HOM...

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Bibliographic Details
Published in:J Virol
Main Authors: Witmer, H, Wiatr, C
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1985
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC254666/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3918174/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.53.2.522-527.1985
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