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Treatment of mice with polyinosinic-polycytidilic polyribonucleotide reduces T-cell involvement in a localized inflammatory response to vaccinia virus challenge.

Mice inoculated intracerebrally with 10(3) PFU of vaccinia virus developed a nonfatal meningitis which was maximal 7 days after challenge. Intravenous administration of an interferon (IFN) inducer, polyinosinic-polycytidilic polyribonucleotide [poly(I)-poly(C)], on days 4 and 6 postinjection was ass...

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Bibliografische gegevens
Gepubliceerd in:J Virol
Hoofdauteurs: Korngold, R, Doherty, P C
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 1985
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC254661/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2578572/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.53.2.489-494.1985
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