Role of the Histone H3 Lysine 4 Methyltransferase, SET7/9, in the Regulation of NF-κB-dependent Inflammatory Genes: RELEVANCE TO DIABETES AND INFLAMMATION

Nuclear factor κ-B (NF-κB)-regulated inflammatory genes, such as TNF-α (tumor necrosis factor-α), play key roles in the pathogenesis of inflammatory diseases, including diabetes and the metabolic syndrome. However, the nuclear chromatin mechanisms are unclear. We report here that the chromatin histo...

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Hlavní autoři: Li, Yan, Reddy, Marpadga A., Miao, Feng, Shanmugam, Narkunaraja, Yee, Jiing-Kuan, Hawkins, David, Ren, Bing, Natarajan, Rama
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2008
Témata:
Transcription, Chromatin, and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546554/
https://ncbi.nlm.nih.gov/pubmed/18650421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802800200
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