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Folding intermediate in the villin headpiece domain arises from disruption of a N-terminal hydrogen-bonded network
The critical role of partially folded intermediates in protein misfolding and amyloid formation has sparked interest in exploring factors that control the formation of these meta-stable species. Recent NMR experiments reported a sparsely populated intermediate of the villin headpiece domain, in whic...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2546516/ https://ncbi.nlm.nih.gov/pubmed/17311386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja0688880 |
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