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Starting at the endophenotype: A role for alpha-CaMKII in schizophrenia?

Using an endophenotype-driven screen, a new study finds that α-calcium/calmodulin kinase II mutant mice exhibit a range of behavioral abnormalities related to schizophrenia. Perhaps most strikingly, this cluster of schizophrenia-related endophenotypes was associated with abnormal neurogenesis in the...

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Autors principals: Frankland, Paul W, Sakaguchi, Masanori, Arruda-Carvalho, Maithé
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546401/
https://ncbi.nlm.nih.gov/pubmed/18803858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-1-5
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