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The Role of the Schizosaccharomyces pombe gar2 Protein in Nucleolar Structure and Function Depends on the Concerted Action of its Highly Charged N Terminus and its RNA-binding Domains

Nonribosomal nucleolar protein gar2 is required for 18S rRNA and 40S ribosomal subunit production in Schizosaccharomyces pombe. We have investigated the consequences of the absence of each structural domain of gar2 on cell growth, 18S rRNA production, and nucleolar structure. Deletion of gar2 RNA-bi...

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Udgivet i:Mol Biol Cell
Principais autores: Sicard, Hélène, Faubladier, Marlène, Noaillac-Depeyre, Jacqueline, Léger-Silvestre, Isabelle, Gas, Nicole, Caizergues-Ferrer, Michèle
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Cell Biology 1998
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25453/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9693363/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.9.8.2011
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