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A 3' end fragment encompassing the transcriptional enhancers of nondefective Friend virus confers erythroleukemogenicity on Moloney leukemia virus.

Nondefective Friend helper murine leukemia virus (Fr-MuLV) induces primarily erythroleukemias in NFS mice, whereas Moloney murine leukemia virus (Mo-MuLV) induces T cell lymphomas. Using molecular clones of these two viruses, we constructed a recombinant in which a 0.62-kilobase fragment encompassin...

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Udgivet i:J Virol
Principais autores: Chatis, P A, Holland, C A, Silver, J E, Frederickson, T N, Hopkins, N, Hartley, J W
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1984
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC254512/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6090701/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.52.1.248-254.1984
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