A 3' end fragment encompassing the transcriptional enhancers of nondefective Friend virus confers erythroleukemogenicity on Moloney leukemia virus.

Nondefective Friend helper murine leukemia virus (Fr-MuLV) induces primarily erythroleukemias in NFS mice, whereas Moloney murine leukemia virus (Mo-MuLV) induces T cell lymphomas. Using molecular clones of these two viruses, we constructed a recombinant in which a 0.62-kilobase fragment encompassin...

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Autors principals: Chatis, P A, Holland, C A, Silver, J E, Frederickson, T N, Hopkins, N, Hartley, J W
Format: Artigo
Idioma:Inglês
Publicat: 1984
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC254512/
https://ncbi.nlm.nih.gov/pubmed/6090701
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