The combination of huperzine A and imidazenil is an effective strategy to prevent diisopropyl fluorophosphate toxicity in mice

Diisopropyl fluorophosphate (DFP) causes neurotoxicity related to an irreversible inhibition of acetylcholinesterase (AChE). Management of this intoxication includes: (i) pretreatment with reversible blockers of AChE, (ii) blockade of muscarinic receptors with atropine, and (iii) facilitation of GAB...

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Main Authors: Pibiri, Fabio, Kozikowski, Alan P., Pinna, Graziano, Auta, James, Kadriu, Bashkim, Costa, Erminio, Guidotti, Alessandro
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2008
Ábhair:
Biological Sciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2544596/
https://ncbi.nlm.nih.gov/pubmed/18784370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807172105
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