The neutrophil gelatinase-associated lipocalin (NGAL), a NF-κB-regulated gene, is a survival factor for thyroid neoplastic cells

NF-κB is constitutively activated in primary human thyroid tumors, particularly in those of anaplastic type. The inhibition of NF-κB activity in the human anaplastic thyroid carcinoma cell line, FRO, leads to an increased susceptibility to chemotherapeutic drug-induced apoptosis and to the blockage...

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Détails bibliographiques
Auteurs principaux: Iannetti, Alessio, Pacifico, Francesco, Acquaviva, Renato, Lavorgna, Alfonso, Crescenzi, Elvira, Vascotto, Carlo, Tell, Gianluca, Salzano, Anna Maria, Scaloni, Andrea, Vuttariello, Emilia, Chiappetta, Gennaro, Formisano, Silvestro, Leonardi, Antonio
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2008
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2544578/
https://ncbi.nlm.nih.gov/pubmed/18768801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710846105
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