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Periplasmic orientation of nascent lipid A in the inner membrane of an Escherichia coli LptA mutant

The core-lipid A domain of Escherichia coli lipopolysaccharide (LPS) is synthesized on the inner surface of the inner membrane (IM) and flipped to its outer surface by the ABC transporter MsbA. Recent studies with deletion mutants implicate the periplasmic protein LptA, the cytosolic protein LptB, a...

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Main Authors: Ma, Bing, Reynolds, C. Michael, Raetz, Christian R. H.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2544538/
https://ncbi.nlm.nih.gov/pubmed/18768814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807028105
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