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Metabolic engineering of a thermophilic bacterium to produce ethanol at high yield

We report engineering Thermoanaerobacterium saccharolyticum, a thermophilic anaerobic bacterium that ferments xylan and biomass-derived sugars, to produce ethanol at high yield. Knockout of genes involved in organic acid formation (acetate kinase, phosphate acetyltransferase, and L-lactate dehydroge...

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Main Authors: Shaw, A. Joe, Podkaminer, Kara K., Desai, Sunil G., Bardsley, John S., Rogers, Stephen R., Thorne, Philip G., Hogsett, David A., Lynd, Lee R.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2544529/
https://ncbi.nlm.nih.gov/pubmed/18779592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801266105
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