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Prolonged administration of a dithiol antioxidant protects against ventricular remodeling due to ischemia-reperfusion in mice

The prolonged production of reactive oxygen species due to ischemia-reperfusion (I/R) is a potential cause of the pathological remodeling that frequently precedes heart failure. We tested the ability of a potent dithiol antioxidant, bucillamine, to protect against the long-term consequences of I/R i...

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Detalhes bibliográficos
Main Authors: Ambler, S. Kelly, Hodges, Yvonne K., Jones, Gayle M., Long, Carlin S., Horwitz, Lawrence D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2544508/
https://ncbi.nlm.nih.gov/pubmed/18689493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01143.2007
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