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Regulation of ERK1/2 by ouabain and Na-K-ATPase-dependent energy utilization and AMPK activation in parotid acinar cells

We previously found that the phosphorylation of ERK1/2 by submaximal concentrations of the muscarinic receptor ligand carbachol was potentiated in rat parotid acinar cells exposed to ouabain, a cardiac glycoside that inhibits the Na-K-ATPase. We now report that this signaling phenomenon involves the...

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Detalhes bibliográficos
Main Authors: Soltoff, Stephen P., Hedden, Lee
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2544437/
https://ncbi.nlm.nih.gov/pubmed/18632735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00140.2008
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