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Loss of heterozygosity for the NF2 gene in retinal and optic nerve lesions of patients with neurofibromatosis 2

Individuals affected with the neurofibromatosis 2 (NF2) cancer predisposition syndrome develop specific ocular lesions. To determine whether these lesions result from altered NF2 gene expression, microdissection and PCR were used to investigate 40 ocular lesions from seven eyes of four NF2 patients...

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Detaylı Bibliyografya
Asıl Yazarlar: Chan, Chi-Chao, Koch, Christian A, Kaiser-Kupfer, Muriel I, Parry, Dilys M, Gutmann, David H, Zhuang, Zhengping, Vortmeyer, Alexander O
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2002
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2543125/
https://ncbi.nlm.nih.gov/pubmed/12210058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.1174
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