Accumulation of Citrullinated Proteins by Up-Regulated Peptidylarginine Deiminase 2 in Brains of Scrapie-Infected Mice : A Possible Role in Pathogenesis

Peptidylarginine deiminases (PADs), which are a group of posttranslational modification enzymes, are involved in protein citrullination (deimination) by the conversion of peptidylarginine to peptidylcitrulline in a calcium concentration-dependent manner. Among the PADs, PAD2 is widely distributed in...

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Main Authors: Jang, Byungki, Kim, Eunah, Choi, Jin-Kyu, Jin, Jae-Kwang, Kim, Jae-Il, Ishigami, Akihito, Maruyama, Naoki, Carp, Richard I., Kim, Yong-Sun, Choi, Eun-Kyoung
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2008
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Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2543080/
https://ncbi.nlm.nih.gov/pubmed/18787103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.080388
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