Gene Silencing of Complement C5a Receptor Using siRNA for Preventing Ischemia/Reperfusion Injury

Ischemia/reperfusion (I/R) injury in organ transplantation significantly contributes to graft failure and is untreatable using current approaches. I/R injury is associated with activation of the complement system, leading to the release of anaphylatoxins, such as C5a, and the formation of the membra...

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Bibliografiske detaljer
Main Authors: Zheng, Xiufen, Zhang, Xusheng, Feng, Biao, Sun, Hongtao, Suzuki, Motohiko, Ichim, Thomas, Kubo, Norihiko, Wong, Arthur, Min, Lisa R., Budohn, Marianne E., Garcia, Bertha, Jevnikar, Anthony M., Min, Wei-Ping
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2008
Fag:
Regular Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2543066/
https://ncbi.nlm.nih.gov/pubmed/18772341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.080103
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