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Establishment and characterization of immortalized Gli-null mouse embryonic fibroblast cell lines

BACKGROUND: Hedgehog (Hh) signaling is a conserved morphogenetic pathway which plays critical roles in embryonic development, with emerging evidence also supporting a role in healing and repair processes and tumorigenesis. The Gli family of transcription factors (Gli1, 2 and 3) mediate the Hedgehog...

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Bibliographic Details
Main Authors: Lipinski, Robert J, Bijlsma, Maarten F, Gipp, Jerry J, Podhaizer, David J, Bushman, Wade
Format: Artigo
Language:Inglês
Published: BioMed Central 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2542994/
https://ncbi.nlm.nih.gov/pubmed/18789160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-9-49
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