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Activation of Rac and Cdc42 by Integrins Mediates Cell Spreading

Adhesion to ECM is required for many cell functions including cytoskeletal organization, migration, and proliferation. We observed that when cells first adhere to extracellular matrix, they spread rapidly by extending filopodia-like projections and lamellipodia. These structures are similar to the R...

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Autori principali: Price, Leo S., Leng, Jie, Schwartz, Martin Alexander, Bokoch, Gary M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC25428/
https://ncbi.nlm.nih.gov/pubmed/9658176
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