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Bound State Residual Dipolar Couplings for Rapidly Exchanging Ligands of His-Tagged Proteins
The study of bound-state conformations of ligands interacting with proteins is important to the understanding of protein function and the design of drugs that alter function. Traditionally, transferred nuclear Overhauser effects (trNOEs), measured from NMR spectra of ligands in rapid exchange betwee...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2542485/ https://ncbi.nlm.nih.gov/pubmed/17385862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja069145h |
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