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Bound State Residual Dipolar Couplings for Rapidly Exchanging Ligands of His-Tagged Proteins

The study of bound-state conformations of ligands interacting with proteins is important to the understanding of protein function and the design of drugs that alter function. Traditionally, transferred nuclear Overhauser effects (trNOEs), measured from NMR spectra of ligands in rapid exchange betwee...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Seidel, Ronald D., Zhuang, Tiandi, Prestegard, James H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2542485/
https://ncbi.nlm.nih.gov/pubmed/17385862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja069145h
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