Efficient termination of vacuolar Rab GTPase signaling requires coordinated action by a GAP and a protein kinase

Rab guanosine triphosphatases (GTPases) are pivotal regulators of membrane identity and dynamics, but the in vivo pathways that control Rab signaling are poorly defined. Here, we show that the GTPase-activating protein Gyp7 inactivates the yeast vacuole Rab Ypt7 in vivo. To efficiently terminate Ypt...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Brett, Christopher L., Plemel, Rachael L., Lobinger, Braden T., Vignali, Marissa, Fields, Stanley, Merz, Alexey J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2008
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2542475/
https://ncbi.nlm.nih.gov/pubmed/18809726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200801001
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg