Efficient termination of vacuolar Rab GTPase signaling requires coordinated action by a GAP and a protein kinase

Rab guanosine triphosphatases (GTPases) are pivotal regulators of membrane identity and dynamics, but the in vivo pathways that control Rab signaling are poorly defined. Here, we show that the GTPase-activating protein Gyp7 inactivates the yeast vacuole Rab Ypt7 in vivo. To efficiently terminate Ypt...

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Bibliografiska uppgifter
Huvudupphovsmän: Brett, Christopher L., Plemel, Rachael L., Lobinger, Braden T., Vignali, Marissa, Fields, Stanley, Merz, Alexey J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2008
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2542475/
https://ncbi.nlm.nih.gov/pubmed/18809726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200801001
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