Urokinase Expression by Tumor Suppressor Protein p53: A Novel Role in mRNA Turnover

Lung carcinoma (H1299) cells deficient in p53 (p53(−/−)) express large amounts of urokinase-type plasminogen activator (uPA) protein and uPA mRNA, and exhibit slower degradation of uPA mRNA than that of p53-expressing nonmalignant Beas2B human airway epithelial cells. Expression of p53 protein in H1...

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Bibliographic Details
Main Authors: Shetty, Praveenkumar, Velusamy, Thirunavukkarasu, Bhandary, Yashodhar P., Shetty, Rashmi S., Liu, Ming-Cheh, Shetty, Sreerama
Format: Artigo
Language:Inglês
Published: American Thoracic Society 2008
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2542451/
https://ncbi.nlm.nih.gov/pubmed/18390474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2007-0406OC
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